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Giotto Biotech Srl offers an extensive catalog of recombinat proteins produced through expression in E. coli and a highly specialized custom production service for proteins.
We are expert in producing proteins uniformly and selectively labeled with stable isotopes, typically 13C, 15N and 2H.
Additionally we can provide ready-to-use NMR reference proteins for solution and solid-state NMR.
Our chemists offer a custom production service for the synthesis of glyco-derivatives and a large variety of glyco-amino acids.
Established experience in the NMR- based metabolomic analysis of biofluids and tissues, metabolic profiling and biomarker discovery.
Our proteins and peptides are accompanied by a quality certification that arises from a strict quality control process that includes: MALDI mass analysis, NMR and SDS-page and/or HR chromatography.
We can offer uniformly and selective labeling upon request (13C, 15N and 2H)
Thanks to a close collaboration with the Magnetic Resonance Center (CERM) at the University of Florence, Giotto has access to an exceptional battery of NMR instrumentation and can therefore provide services in NMR metabolomics and statistical analysis, NMR protein structure determination, and screening of libraries against protein targets.