MMP1hpx

MMP1 Hemopexin Like domain

Human, recombinant.
residues 274-469, swissprot accession P03956
MW = 23200 Da.
EC # 3.4.24.7
CAT # G04MP01H

Packaging and prices - Technical Details - References

Packaging and Prices

Unlabeled Protein
Catalog n° Labeling Q.ty Price (€)
G04MP01H none 10 µg 200.00
G04MP01H none 5 x 10µg 400.00

Special prices for bulk quantities, or labelled samples, available upon request.

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Description
MW = 23.2 kDa calculated. Hemopexin-Like Domain of MMP1 (Interstitial collagenase, matrix metalloproteinase 1), cloned from human cDNA, expressed in E. coli. The protein consists of the hemopexin-like domain of human MMP-1 (residues 274-469, swissprot accession P03956).

Sequence
                             280        290        300
                       M-TPKACDS KLTFDAITTI RGEVMFFKDR 
       310        320        330        340        350
FYMRTNPFYP EVELNFISVF WPQLPNGLEA AYEFADRDEV RFFKGNKYWA 
       360        370        380        390        400
VQGQNVLHGY PKDIYSSFGF PRTVKHIDAA LSEENTGKTY FFVANKYWRY 
       410        420        430        440        450
DEYKRSMDPG YPKMIAHDFP GIGHKVDAVF MKDGFFYFFH GTRQYKFDPK 
       460 
TKRILTLQKA NSWFNCRKN

Purity
> 95% by SDS-PAGE. The protein was observed as a single band migrating at a molecular weight between 20 and 30 kDa.

Usage
Enzyme kinetic studies, cleavage of target substrates and screening of inhibitors.

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