MMP2hpx

MMP2 HEMOPEXYIN LIKE DOMAIN

Human, recombinant.
residues 467-660, swissprot accession P08253
MW = 22200 Da.
EC # 3.4.24.24
CAT # G04MP02H

Packaging and prices - Technical Details - References

Packaging and Prices

Unlabeled Protein
Catalog n° Labeling Q.ty Price (€)
G04MP02H none 10 µg 200.00
G04MP02H none 5 x 10µg 400.00

Special prices for bulk quantities, or labelled samples, available upon request.

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Description
MW = 22.2 kDa. Hemopexin-Like Domain (C domain) of MMP2, cloned from human cDNA, expressed in E. coli. The enzyme consists of the hemopexin-like domain of human MMP-2 (residues 467-660, swissprot accession P08253).

Sequence
                  470        480        490        500
               M-EICK QDIVFDGIAQ IRGEIFFFKD RFIWRTVTPR 
       510        520        530        540        550
DKPMGPLLVA TFWPELPEKI DAVYEAPQEE KAVFFAGNEY WIYSASTLER 
       560        570        580        590        600
GYPKPLTSLG LPPDVQRVDA AFNWSKNKKT YIFAGDKFWR YNEVKKKMDP 
       610        620        630        640        650
GFPKLIADAW NAIPDNLDAV VDLQGGGHSY FFKGAYYLKL ENQSLKSVKF 
       660
GSIKSDWLGC

Purity
> 95% by SDS-PAGE. The protein was observed as a single band migrating at a molecular weight below 20 kDa.

Usage
Enzyme kinetic studies, cleavage of target substrates and screening of inhibitors.

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References
U.M. Wallon and C.M.Overall. J Biol. Chem. 1997, 272(11), 7473.

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